FITC标记的γ2肌动蛋白抗体
产品名称： FITC标记的γ2肌动蛋白抗体
英文名称： Anti-ACTG2/FITC
产品编号： HZ-12368R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ACTG2/FITC Conjugated antibody
FITC标记的γ2肌动蛋白抗体
| 英文名称 | Anti-ACTG2/FITC |
| 中文名称 | FITC标记的γ2肌动蛋白抗体 |
| 别 名 | ACT; ACTA3; ACTE; Actin gamma 2 smooth muscle enteric; Actin gamma enteric smooth muscle; Actin like protein; ACTL3; ACTSG; Alpha actin 3; Gamma 2 actin; Smooth muscle gamma actin; ACTH_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 细胞骨架 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ACTG2/Gamma 2 actin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N terminal peptides. Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Subunit: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Subcellular Location: Cytoplasm: cytoskeleton Post-translational modifications: Oxidation of Met-45 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. Methionine sulfoxide is produced stereospecifically, but it is not known whether the (S)-S-oxide or the (R)-S-oxide is produced (By similarity). Similarity: Belongs to the actin family. Database links: Entrez Gene: 72 Human Entrez Gene: 11468 Mouse Entrez Gene: 25365 Rat Entrez Gene: 396084 Chicken Entrez Gene: 281595 Cow Omim: 102545 Human SwissProt: P63270 Chicken SwissProt: Q5E9B5 Cow SwissProt: P63267 Human SwissProt: P63268 Mouse SwissProt: P63269 Rat Unigene: 516105 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
肌动蛋白是高度保守的蛋白质，参与各种类型的细胞运动和维持细胞骨架。在脊椎动物中已经鉴定出三种类型的肌动蛋白，α、β和γ。α-肌动蛋白存在于肌肉组织中，是收缩装置的主要组成部分。β和γ在大多数细胞类型中共存，作为细胞骨架的组成部分和内部细胞运动的介质。该基因编码肌动蛋白γ2；在肠组织中发现平滑肌肌动蛋白。选择性剪接导致多个转录变体编码不同的亚型。基于与相关肌动蛋白肽裂解的相似性，该基因的成熟蛋白是通过去除两个N端肽形成的。